This paper was aimed to report the 3D finite element analysis simulation of laser welding process of Ti6Al4V 1.7 mm sheets in butt joint in order to predict the temperature distribution, hardness, and weld geometry. The butt-joint welds were made using CO2 laser with the maximum power of 2.2 kW in the continuous wave mode. A part of the experimental work was carried out to verify the weld geometry with specific weld parameters including power, speed, and focal position. Another part investigated the effect of focal position on the weld bead geometry. Subsequently, the shapes of the molten pool were predicted by the numerical analysis method and compared with the results obtained through the experimentation, which led to finding a good agreement.